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. 2016 Apr 29;6:25176. doi: 10.1038/srep25176

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(A) Plasma IL-6 levels. ST-ISO had significantly higher (P < 0.05) IL-6 levels as compared to the ST-PH in the acute survival cohort. (B) In the chronic survival group there was no main effect of SI or any interaction [(F (1, 17) = 0.2678; P = 0.6115] between stroke and housing condition. (C) Total BDNF expression and activity was higher in PH animals and significant interaction [F 1, 8 = 7.13 P = 0.0238] between housing and surgery (stroke) was found in mice.