Figure 5. Mast cell counts are reduced after Sec^PBMC and Apo-Sec^PBMC treatment.

Mast cells are found in wounds if derailed scarring occurs. (a) Mast cell tryptase-positive cells were found in the superficial layers of the dermis. Arrows indicate mast cells. 400× magnification, scale bar: 50 μm. (b) We found no difference in mast cell numbers 2 days after surgery. (c) On day 5 we observed a non-significant trend towards fewer mast cells in wounds treated with Sec^PBMC or Apo-Sec^PBMC compared to the control groups. (d) On day 10, this difference was more pronounced. The numbers in the diagrams represent the sum of four randomly chosen sections per wound. Error bars indicate SEM. n = 6.