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. 2016 Apr 29;6:25264. doi: 10.1038/srep25264

Figure 3. Chromothrypsis of chromosome 4 (1/71 tumors) and 13 (5/71 tumors).

Figure 3

Segmented (orange lines) somatic copy number estimates (black dots, Log2-ratios, Y-axis) are plotted along genomic coordinates (X-axis). Chromothrypsis, characterized by clustered chromosomal alterations, was observed for 6 chromosomes in five different tumors. One tumor (T64) showed chromothrypsis at both chromosome 4 and 13. Blue rectangles indicate the RB1 locus.