Table 1. Baseline characteristics and microbiome reads.
| Variable | TA | SSA/P | CRC | P-value |
|---|---|---|---|---|
| n | 8 | 10 | 8 | |
| Age, year, median (IQR) | 68 (55–74) | 54 (49–66) | 63 (60–76) | 0.119 |
| Male, n (%) | 6 (75.0) | 5 (50.0) | 7 (87.5) | 0.244 |
| Tumor location, n (%) | 0.006 | |||
| Proximal colon | 5 (62.5) | 7 (70.0) | 0 (0.0) | |
| Distal colon | 3 (37.5) | 3 (30.0) | 8 (100.0) | |
| Read count, median (IQR) | 5,540 (3,150–6,875) | 6,162 (4,483–7,394) | 4,969 (1,642–6,132) | 0.247 |
| OTU, median (IQR) | 45.0 (33.3–71.5) | 44.0 (28.0–74.5) | 55.0 (33.8–80.3) | 0.847 |
| Chao1 estimator, median (IQR) | 46.8 (36.9–88.5) | 48.6 (30.8–81.0) | 65.4 (44.8–88.8) | 0.551 |
| Shannon’s diversity index, median (IQR) | 3.22 (2.89–3.75) | 3.51 (2.55–4.00) | 3.56 (2.52–4.21) | 0.912 |
| Simpson’s diversity index, median (IQR) | 0.82 (0.78–0.86) | 0.84 (0.70–0.90) | 0.84 (0.69–0.91) | 0.872 |
TA, tubular adenoma; SSA/P, sessile serrated adenoma/polyp; CRC, colorectal cancer; OTU, operational taxonomic unit; IQR, interquartile rnage.