Table 2.
Genes differentially expressed in tumors from normal-weight compared to obese women. Genes in bold remained statistically significant when age at diagnosis and self-described ethnicity were included with BMI in ANOVA
| All BMI groupsa | Normal-weight vs obese | |||
|---|---|---|---|---|
| Gene Symbol | Probe | P-value | P-value | Fold-change (normal-weight/obese) |
| ABCA3 | 204343_at | 4.5E-05 | 9.8E-06 | 0.66 |
| ACSL1 | 201963_at | 0.0001 | 3.0E-05 | 1.48 |
| APOD | 201525_at | 0.0002 | 2.3E-05 | 2.36 |
| AVL9 | 212471_at | 4.9E-05 | 9.7E-06 | 0.82 |
| BUB1 | 209642_at | 1.6E-05 | 6.5E-05 | 0.64 |
| CCNB2 | 202705_at | 2.8E-05 | 1.4E-05 | 0.64 |
| CDC25C | 205167_s_at | 0.0002 | 7.4E-05 | 0.67 |
| CDC6 | 203968_s_at | 0.0002 | 8.5E-05 | 0.72 |
| CENPA | 204962_s_at | 8.9E-05 | 3.2E-05 | 0.59 |
| CENPF | 207828_s_at | 2.3E-05 | 6.7E-05 | 0.65 |
| CEP55 | 218542_at | 7.6E-05 | 5.1E-05 | 0.60 |
| CHEK1 | 205394_at | 0.0002 | 5.1E-05 | 0.70 |
| CORO2B | 209789_at | 0.0002 | 3.9E-05 | 1.27 |
| DENND1A | 219763_at | 3.3E-07 | 5.0E-08 | 0.66 |
| EXO1 | 204603_at | 0.0003 | 8.8E-05 | 0.80 |
| EZH2 | 203358_s_at | 3.2E-05 | 1.5E-05 | 0.68 |
| FLRT2 | 204359_at | 0.0005 | 8.6E-05 | 1.60 |
| FOXM1 | 202580_x_at | 1.2E-05 | 8.9E-06 | 0.67 |
| GTSE1 | 204317_at | 0.0003 | 7.7E-05 | 0.83 |
| IGF1 | 209542_x_at | 2.4E-05 | 6.2E-06 | 1.75 |
| 211577_s_at | 3.5E-05 | 1.0E-06 | 1.72 | |
| KIF14 | 206364_at | 1.5E-05 | 1.0E-05 | 0.70 |
| KIF18B | 222039_at | 9.1E-06 | 1.1E-05 | 0.67 |
| KIF2C | 209408_at | 0.0002 | 3.0E-05 | 0.66 |
| KIF4A | 218355_at | 0.0001 | 5.5E-05 | 0.64 |
| KLHL12 | 219931_s_at | 0.0005 | 8.4E-05 | 0.79 |
| MELK | 204825_at | 4.0E-06 | 2.2E-06 | 0.58 |
| MKI67 | 212022_s_at | 0.0007 | 3.5E-05 | 0.69 |
| 212021_s_at | 0.0002 | 3.4E-05 | 0.71 | |
| NUDT13 | 214136_at | 0.0005 | 9.3E-05 | 0.74 |
| OGN | 218730_s_at | 0.0003 | 5.4E-05 | 2.05 |
| OIP5 | 213599_at | 7.5E-05 | 4.5E-05 | 0.67 |
| PARP1 | 208644_at | 0.0004 | 6.7E-05 | 0.81 |
| PDIA4 | 211048_s_at | 0.0005 | 9.5E-05 | 0.80 |
| PRC1 | 218009_s_at | 0.0002 | 7.3E-05 | 0.66 |
| PSMD4 | 200882_s_at | 0.0005 | 9.1E-05 | 0.83 |
| RBMS3 | 206767_at | 0.0003 | 5.9E-05 | 1.28 |
| SCCPDH | 201826_s_at | 0.0005 | 9.8E-05 | 0.73 |
| SERPINB13 | 216258_s_at | 3.9E-05 | 2.6E-05 | 0.93 |
| TADA2A | 209938_at | 0.0005 | 9.1E-05 | 0.84 |
| TIMELESS | 203046_s_at | 1.1E-05 | 1.5E-05 | 0.75 |
| TYMS | 202589_at | 6.5E-06 | 3.9E-06 | 0.65 |
| WHSC1 | 209054_s_at | 0.0003 | 8.6E-05 | 0.81 |
| ZWINT | 204026_s_at | 8.6E-06 | 3.1E-06 | 0.67 |
aGenes that differed significantly in expression levels when ANOVA was performed across normal weight, overweight and obese groups