Table 3.
Differentially regulated pathways between tumors from normal-weight and obese women
| KEGG pathway | Enrichment score | Enrichment P-value | % Genes present in pathway |
|---|---|---|---|
| Cell cycle | 10.9 | 1.8E-005 | 4.3 |
| p53 signaling pathway | 10.4 | 3.1E-005 | 6.5 |
| Progesterone-mediated oocyte maturation | 9.6 | 7.0E-005 | 5.3 |
| Oocyte meiosis | 8.7 | 0.0002 | 4.2 |
| One carbon pool by folate | 3.1 | 0.0456 | 6.7 |
| Mismatch repair | 2.7 | 0.0692 | 4.3 |
| Base excision repair | 2.4 | 0.0951 | 3.1 |
| Transcriptional misregulation in cancer | 2.3 | 0.0962 | 1.2 |
| ABC transporters | 2.2 | 0.1064 | 2.8 |
| Aldosterone-regulated sodium reabsorption | 2.1 | 0.1175 | 2.5 |
| Fatty acid metabolism | 2.1 | 0.1231 | 2.4 |
| Lysine degradation | 2.1 | 0.1258 | 2.3 |
| Proteasome | 2.1 | 0.1285 | 2.4 |
| mTOR signaling pathway | 2.0 | 0.1394 | 2.1 |