Table 3. Top 10 up-regulated transcripts in bladder tissue from turpentine group, ranked by mRNA fold change normalised to naive values.
Data presented as mean fold change (95% confidence interval), n=3–4 animals/group.
Acute Bladder Inflammation | Repeated Bladder Inflammation | |||||
---|---|---|---|---|---|---|
Rank | Gene | Fold Change | 95% Confidence
Interval |
Gene | Fold Change | 95% Confidence
Interval |
1 | NOS2 | 159110.28 | -127366.6–445587.2 | CCL12 | 169.65 | 67.05–272.25 |
2 | PROK2 | 11060.01 | -12741.5–34861.5 | CTLA-8 | 75.098 | -56.21–206.4 |
3 | CXCL2 | 3679.32 | -4618.0–11976.7 | CXCL17 | 71.2 | -22.64–165.03 |
4 | CCL3 | 2541.99 | -1417.4–6501.3 | CXCL11 | 53.27 | -71.05–177.6 |
5 | IL-1α | 1827.32 | -2717.6–6372.2 | NOS2 | 14.2 | -9.46–37.87 |
6 | IL-1β | 403.78 | -328.2–1135.7 | BDNF | 11.9 | -2.06–25.86 |
7 | CSF3 | 350.52 | -269.9–971.0 | CXCL2 | 9.94 | -9.78–29.65 |
8 | CXCL3 | 254.33 | -131.8–640.5 | PROK2 | 9.12 | -10.24–28.49 |
9 | IL-10 | 222.75 | -399.6–845.1 | IL-21 | 8.88 | -17.20–34.96 |
10 | IL-6 | 153.21 | -42.8–349.3 | IL-1β | 8.63 | 4.62–12.65 |