Table 1.

Point mutations predicted to introduce amino acid changes

GeneName	Chr	GRCh37 position	Ref>Alt	GenBank accession	Predicted effect	Class	WGS reads (mut/total)		VAF in tumor %
							Tumor	Normal
ATP6AP1	chrX	153664066	C>A	NM_001183	Y414*	Nonsense	18/30	0/16	60
GFRA2	chr8	21608169	G>A	NM_001495	S242F	Missense	18/49	0/27	37
TXNDC16	chr14	52937263	A>C	NM_020784	L483*	Nonsense	12/40	0/44	30
BRD7	chr16	50353864	G>A	NM_001173984	R613*	Nonsense	7/34	0/27	21
MAP3K9	chr14	71199588	G>A	NM_033141	T847M	Missense	8/26	0/18	31
PPFIBP2	chr11	7670871	C>T	NM_003621	R703W	Missense	11/35	0/29	31
UBE2H	chr7	129497389	C>T	NM_003344	C87Y	Missense	12/47	0/47	26
MXRA5	chrX	3240233	G>A	NM_015419	R1165W	Missense	6/32	0/22	19
ITGA1	chr5	52225500	G>A	NM_181501	E914K	Missense	9/65	0/33	14

WGS, whole-genome sequencing; VAF, variant allele frequency.