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. 2015 Oct;1(1):a000422. doi: 10.1101/mcs.a000422

Figure 1.

Figure 1.

(A) Pedigree structure of a simplex autism family. For a family to be classified as a simplex autism family, it has to be composed of one affected child and at least one unaffected sibling, and both parents should not have obvious autism. Probands and siblings can be either males or females. (B) K21 proband showing no dysmorphology. (C) Analyzed pedigrees. Two of the families have male probands and unaffected male siblings (K21 and SSC_12605), whereas the third family has a male proband and a female unaffected sibling (SSC_12596).