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. Author manuscript; available in PMC: 2016 Apr 29.
Published in final edited form as: Atherosclerosis. 2015 Jul 4;242(1):56–64. doi: 10.1016/j.atherosclerosis.2015.06.055

Fig. 1.

Fig. 1

Synergistic effects of pioglitazone and losartan, on renal injury-induced acceleration in atherosclerosis. Apolipoprotein E knockout mice underwent sham operation (Sham, n = 10) or uninephrectomy (UNx, n = 40) and were divided into four groups: no treatment (UNx, n = 10), pioglitazone (UNx + Pio, n = 10), losartan (UNx + Los, n = 10), and pioglitazone together with losartan (UNx + Pio/Los, n = 10). Atherosclerosis was assessed on cryosections from the proximal aorta and stained with Oil-Red-O. **p < 0.05 vs. UNx, and #p < 0.05 vs. UNx + Pio/Los.