TABLE 2.
Prostate Cancer HRQOL Outcome Measure Ratings and Clinical Utility
| Measure | Rating | Clinical Utility |
|---|---|---|
| Prostate cancer-specific HRQOL measures | ||
| EORTC QLQ-P25 | 4 | Easy to use, normative data, good psychometric properties |
| EPIC | 4 | Easy to use, no normative data, good psychometric properties |
| FACT-P | 4 | Easy to use, normative data, good psychometric properties |
| UCLA-PCI | 4 | Easy to use, no normative data, good psychometric properties |
| PORPUS | 2A | Limited psychometric property information, used in limited studies, difficulty with scoring, need a trained interviewer |
| PROSQOLI | 2A | Limited psychometric property information, difficulty with scoring, used in limited studies |
| QOLM P14 | 2A | Difficulty with scoring, used in limited studies, specific to advanced prostate cancer |
| Southwest Oncology Group Prostate treatment symptoms measure | 2A | Limited psychometric property information, typically used in conjunction with Southwest Oncology Group Trials, not widely used outside of these trials |
| PCTO-Q | 1 | Time consuming (41 items), limited psychometric property information, unclear information for scoring |
| General cancer HRQOL measures | ||
| EORTC QLQ-C30 | 4 | Easy to use, normative data, good psychometric properties |
| FACT-G | 4 | Easy to use, normative data, good psychometric properties |
| CARES | 2A | Time consuming (139 or 59 items), complex scoring, no normative data for prostate cancer |
| Ferrans and Powers QLI-CV | 2A | Time consuming (66 items), no normative data for prostate cancer, difficulty with scoring |
| FLIC | 2A | No normative data for prostate cancer, difficulty with scoring |
| General HRQOL measures | ||
| SF-36, -12, and –8 | 4 | Easy to use, normative data, good psychometric properties |
| EQ-5D | 2A | Possible licensing fees, no normative data for prostate cancer |
| HUI | 2A | Limited psychometric property information, difficulty with scoring |
| QWB | 2A | Limited psychometric property information, no normative data for prostate cancer, difficulty with scoring |
| Rotterdam Symptom Checklist | 2A | Time consuming (39 items), no normative data for prostate cancer. |
| WHOQoL | 2A | 100-time consuming, difficulty with scoring, no normative data for prostate cancer BREF—difficulty with scoring, no normative data for prostate cancer |
Abbreviations: CARES, Cancer Rehabilitation Evaluation System; EORTC, European Organization for the Research and Treatment of Cancer; EORTC QLQ-P25, European Organization for Research and Treatment of Cancer Quality of Life Questionnaire–Prostate 25; EORTC QLQ-C30, European Organization for Research and Treatment of Cancer Quality of Life Questionnaire–Cancer; EPIC, Expanded Prostate Cancer Index Composite; FACT-G, Functional Assessment of Cancer Therapy–General; FACT-P, Functional Assessment of Cancer Therapy-Prostate; FLIC, Functional Living Index Cancer; HUI, Health Utilities Index; PCTO-Q, Prostate Cancer Treatment Outcome Questionnaire; PORPUS, Prostate Cancer Specific Quality of Life; PROSQOLI, Prostate Cancer Specific Quality of Life Instrument; QLI-CV, Quality of Life Index–Cancer Version; QOLM P14, Quality of Life Module–Prostate 14; QWB, Quality Well Being; UCLA-PCI, UCLA–Prostate Cancer Index; WHOQoL, World Health Organization Quality of Life.