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. Author manuscript; available in PMC: 2016 Apr 29.
Published in final edited form as: Nature. 2015 Oct 12;526(7574):591–594. doi: 10.1038/nature15377

Extended Data Figure 6. Direct competition between YTHDF2 and FTO in m6A binding.

Extended Data Figure 6

a, Synthesized mRNA with m6A was incubated with FTO (2 μg) in the presence of increasing amount of YTHDF2 (0, 0.5, 1, 2 μg), followed by RNA pulldown and immunoblotting. b, Synthesized mRNA with m6A was incubated with FTO (1 μg in top panel and 2 μg in bottom panel) in the absence of presence of YTHDF2 (4 μg), followed by m6A dot blotting.