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. 2016 May;44(5):720–731. doi: 10.1124/dmd.116.069419

Fig. 7.

Fig. 7.

GL markedly attenuates serum ALT and AST levels in both wild-type and Cyp2e1-null mice. (A, B) Serum ALT and AST levels in wild-type mice. (C, D) Serum ALT and AST levels in Cyp2e1 null mice. Control, saline-treated mice; GL 50, only GL 50 mg/kg-treated mice; APAP, saline/APAP-treated mice; GL50 + APAP, GL 50 mg/kg (i.p.)/APAP-treated mice. WT, wild-type. Data are expressed as mean ± S.E.M., n = 5 mice in each group. #P < 0.05, ##P < 0.01, and ###P < 0.001 versus control mice. *P < 0.05, **P < 0.01, and ***P < 0.001 versus APAP-overdosed mice.