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CYP26A1 and CYP26B1 IC50 values for retinoic acid receptor agonists and their derivatives (95% confidence interval shown in parentheses)
| Retenoic Acid Receptor Agonist | CYP26A1 IC50 | CYP26B1 IC50 |
|---|---|---|
| μM | μM | |
| AM80 | 12 (8.1–18) | 6.6 (2.3–19) |
| AM580 | 5.6 (3.0–10) | 2.2 (1.4–3.2) |
| BMS753 | 18 (4.4–76) | 28 (21–37) |
| BMS961 | 14 (9.6–20) | 31 (15–63) |
| Tazarotenic Acid | 6.1 (3.2–12) | 0.13 (0.09–0.19) |
| TTNPB | 3.7 (1.4–9.8) | 3.4 (2.2–5.2) |
