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. 2016 May;357(2):248–257. doi: 10.1124/jpet.115.229542

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Fig. 8. — Correlation between cocaine-seeking behavior, β-endorphin, and POMC expression. (A) Strong negative correlation between plasma concentrations of β-endorphin and cocaine-seeking behavior during reinstatement, r = –0.617, *P < 0.05. (B) Weak positive correlation, but nonsignificant, between plasma concentrations of β-endorphin and POMC expression, r = .361, P = 0.187 Finally, (C) demonstrates the lack of correlation between cocaine-seeking behavior during reinstatement and POMC expression, r = 0.214, P = 0.440; n = 15 for all correlation analysis.