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. 2016 Apr 29;10(4):e0004646. doi: 10.1371/journal.pntd.0004646

Table 3. Symptom frequency in subjects with co-infection, dengue virus (DENV) mono-infection, and Plasmodium mono-infection.

Symptoms Co-infection n/total (%) DENV n/total (%) Plasmodium n/total (%) p value*
Abdominal pain 8/17 (47%) 15/51 (29%) 21/44 (48%) 0.1033
Epistaxis*** 1/17 (7%) 1/51 (2%) 0/44 (0%) 0.282
Prostration 2/15 (13%) 2/51 (4%) 3/41 (7%) 0.5625
Asthenia 9/16 (56%) 23/51 (45%) 18/44 (41%) 0.3873
Chills 15/17 (88%) 48/51 (94%) 41/44 (93%) 0.7081
Malaise 15/16 (94%) 50/51 (98%) 41/41 (100%) 0.4286
Pallor 5/16 (31%) 11/51 (22%) 18/44 (41%) 0.2133
Rash 2/16 (13%) 2/51 (4%) 0/41 (0%) 0.0445
Arthralgia 14/16 (88%) 48/51 (94%) 39/44 (87%) 0.4844
Myalgia 13/16 (81%) 45/51 (88%) 30/44 (68%) 0.031**
Diarrhea 4/17 (24%) 7/51 (14%) 7/44 (16%) 0.6376
Nausea 13/17 (76%) 36/51 (71%) 28/44 (64%) 0.4135
Vomiting 8/17 (47%) 23/51 (45%) 16/44 (36%) 0.2949
Rhinorrhea 2/16 (13%) 4/50 (8%) 6/44 (14%) 0.8348
Cough 5/16 (31%) 5/51 (10%) 15/44 (34%) 0.010**
Expectoration 1/16 (6%) 2/51 (4%) 3/44 (7%) 0.8648
Headache 16/16 (100%) 51/51 (100%) 42/44 (95%) 0.1837
Eye pain 10/15 (67%) 40/51 (78%) 28/41 (68%) 0.455

* Conditional logistic regression, matched analyses

** Dengue virus mono-infection different from Plasmodium mono-infection

*** No recorded cases of gum bleeding, hematochezia, or hematuria