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. Author manuscript; available in PMC: 2016 Apr 29.
Published in final edited form as: Ann Appl Stat. 2015 Nov 2;9(3):1571–1600. doi: 10.1214/15-AOAS844

Algorithm 3.

DAWN algorithm

1. Obtain gene specific p-values.
2. Estimate the gene network using the PNS algorithm (Algorithm 1).
3. Incorporate the information from steps 1 and 2 into the HMRF model and estimate the parameters of the HMRF model (Algorithm 2).
4. Apply the Bayesian FDR correction to determine the risk genes [equation (3.5)].