Fig. 3.

Mean arterial pressure (MAP), pulsatile arterial pressure (AP), and heart rate (HR) in two rats 2 weeks after T4 clip compression spinal cord injury: after intrathecal treatment with control IgG (A) and after intrathecal treatment with an anti-NGF treatment (trkA-IgG) (B). Colon distension for 60 s (onset and duration marked with a thick line) stimulated an increase in AP and MAP and a decrease in HR in the control treated rat. In contrast, colon distension caused only a modest increase in AP and MAP after anti-NGF treatment (B).

Adapted, with permission, from Marsh et al. (2002).