Skip to main content
. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Thorac Surg Clin. 2016 May;26(2):215–228. doi: 10.1016/j.thorsurg.2015.12.009

Figure 2.

Figure 2

Tumor targeting of nanoparticles. A. Permeable vasculature from endothelial cell gaps leads to passive diffusion of small molecules and nanocarriers into the tumor microenvironment. Due to their size, nanocarriers do not diffuse out as easily and hence accumulate within the tumor tissue. B. Specific receptors on nanocarriers target ligands on the tumor tissue. From Danhier F, Oliver F, Veronique P. To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery. 2010;148(2):135–146; with permission.