. Author manuscript; available in PMC: 2017 May 1.

Published in final edited form as: J Am Acad Child Adolesc Psychiatry. 2016 Mar 3;55(5):359–366. doi: 10.1016/j.jaac.2016.02.013

Table 2.

Cumulative Incidence and 95% CIs by Age 14 for Depression, Anxiety, Autism Spectrum Disorders (ASDs) and Attention- Deficit/Hyperactivity Disorders (ADHD) in Offspring of Mothers Using Selective Serotonin Reuptake Inhibitors (SSRIs) During Pregnancy, Offspring of Mothers With Psychiatric Disorder but no Antidepressant Use, Offspring of Mothers Discontinuing SSRI Use Prior to Pregnancy, and in Unexposed Offspring

	SSRI Exposed n=15,729		Psychiatric Disorder, no medication exposed n=9,651		SSRI Discontinued Group n=7,980		Unexposed n=31,394
Offspring diagnosis	n	Cumulative incidence,^a % (95% CI)	n	Cumulative incidence,^a % (95% CI)	n	Cumulative incidence,^a % (95% CI)	n	Cumulative incidence,^a % (95% CI)
Depression	60	8.2 (3.1-13.3)	30	1.9 (0.9-2.9)	25	2.8 (1.4-4.3)	30	1.6 (0.8-2.4)
Anxiety	65	3.1 (1.8-4.3)	39	2.3 (1.3-3.2)	27	2.6 (0.9-4.2)	62	1.1 (0.6-1.6)
ASD	88	2.7 (1.9-3.5)	79	2.3 (1.9-2.8)	40	1.3 (0.8-1.8)	100	1.1 (0.8-1.4)
ADHD	160	4.9 (3.8-6.0)	137	4.2 (3.5-5.0)	93	4.1 (3.1-5.1)	124	1.7 (1.3-2.0)

Note: Depression included depressive disorders and unspecified affective disorders (International Classification of Diseases 10^th Revision [ICD-10] code: F32-39). ICD-10 code for anxiety: F40-41. ICD-10 code for ASD: F84 (excluding Rett's syndrome, F84.2). ADHD (ICD-10 F90).

Kaplan-Meier method.