Figure 2.

Sources of variance in radical prostatectomies (RPs) and biopsy (BX) samples. A: Hierarchical clustering of samples from tumor and benign tissues from BX and RP origins. The two main clusters are generated on the basis of the origin (BX versus RP), containing both benign and tumor samples. Additional clusters are obtained on the basis of the tissue type (tumor versus benign). B and C: Principal component analysis (PCA) shows that sample origin (BX versus RP) contributes the biggest variation and that tissue type (tumor versus benign) contributes less to the total variation.