Table 2.
Lipid lowering treatments after the guideline change
| Before medication titration | After medication titration | |||||
|---|---|---|---|---|---|---|
| Intervention | Control | P-value | Intervention | Control | P-value | |
| No treatment (%) | 12.9 | 11.0 | 0.68 | 4.0 | 9.0 | 0.15 |
| Simvastatin (%) | 33.7 | 52.0 | 0.009 | 21.8 | 51.0 | <0.001 |
| Simvastatin 10 mg | 2.0 | 5.0 | 0.24 | 1.0 | 6.0 | 0.05 |
| Simvastatin 20 mg | 14.9 | 25.0 | 0.07 | 9.9 | 21.0 | 0.03 |
| Simvastatin 40 mg | 16.8 | 22.0 | 0.35 | 10.9 | 24.0 | 0.01 |
| Atorvastatin (%) | 44.6 | 35.0 | 0.17 | 56.4 | 38.0 | 0.009 |
| Atorvastatin 20 mg | 6.9 | 13.0 | 0.15 | 5.0 | 14.0 | 0.03 |
| Atorvastatin 40 mg | 25.7 | 19.0 | 0.25 | 29.7 | 21.0 | 0.16 |
| Atorvastatin 60 mg | 0 | 1.0 | 0.31 | 0 | 1.0 | 0.31 |
| Atorvastatin 80 mg | 11.9 | 2.0 | 0.006 | 22.8 | 2.0 | <0.001 |
| Rosuvastatin (%) | 4.0 | 0 | 0.04 | 8.9 | 0 | 0.002 |
| Rosuvastatin 20 mg | 3.0 | 0 | 0.08 | 3.0 | 0 | 0.08 |
| Rosuvastatin 40 mg | 1.0 | 0 | 0.32 | 5.9 | 0 | 0.01 |
| Othera (%) | 5.0 | 2.0 | 0.25 | 7.9 | 2.0 | 0.05 |
aPravastatin 40 mg, combination of atorvastatin 80 mg and ezetimib 10 mg or combination of rosuvastatin 40 mg and ezetimib 10 mg