Table 2.
Correlation of high NNMT expression with clinical attributes in gastric cancer
| Groups | NO. | NNMT | Pearson χ2 | P-value | |
|---|---|---|---|---|---|
|
|
|||||
| High no. | % | ||||
| Gender | 3.832 | 0.061 | |||
| Male | 464 | 246 | 53.0 | ||
| Female | 153 | 95 | 62.1 | ||
| Age | 1.978 | 0.161 | |||
| ≤60 years | 247 | 128 | 51.8 | ||
| >60 years | 370 | 213 | 57.6 | ||
| Histological type | 4.431 | 0.351 | |||
| Tubular | 512 | 300 | 57.6 | ||
| Hybrid | 7 | 3 | 42.9 | ||
| Mucinous | 28 | 11 | 39.3 | ||
| Signet ring cell | 21 | 11 | 52.4 | ||
| Othersa | 13 | 8 | 61.5 | ||
| Differentiation | 5.066 | 0.079 | |||
| High | 32 | 12 | 37.5 | ||
| Moderate | 157 | 87 | 55.4 | ||
| Low | 383 | 222 | 58 | ||
| Othersb | |||||
| Primary tumor size | 33.468 | <0.001* | |||
| Tis | 33 | 17 | 21.2 | ||
| T1 | 62 | 28 | 45.2 | ||
| T2 | 120 | 55 | 45.8 | ||
| T3 | 345 | 214 | 62 | ||
| T4 | 48 | 34 | 70.8 | ||
| Lymph node metastasis | 33.486 | <0.001* | |||
| N0 | 238 | 101 | 42.4 | ||
| N1 | 108 | 60 | 55.6 | ||
| N2 | 117 | 74 | 63.2 | ||
| N3 | 145 | 103 | 71 | ||
| Distant metastasis | 9.130 | 0.002* | |||
| M0 | 580 | 312 | 53.8 | ||
| M1 | 38 | 30 | 78.9 | ||
| TNM stage | 46.134 | <0.001* | |||
| 0 | 34 | 9 | 26.5 | ||
| I | 119 | 44 | 37.0 | ||
| II | 200 | 112 | 56.0 | ||
| III | 217 | 143 | 65.9 | ||
| IV | 38 | 30 | 78.9 | ||
| Preoperative CEA, ng/ml | 2.517 | 0.284 | |||
| ≤5 | 263 | 136 | 51.7 | ||
| >5 | 74 | 44 | 59.5 | ||
| Unknown | 281 | 162 | 57.7 | ||
| Preoperative CA199, U/ml | 2.590 | 0.274 | |||
| ≤37 | 276 | 143 | 51.8 | ||
| >37 | 50 | 30 | 60 | ||
| Unknown | 292 | 169 | 57.9 | ||
P<0.05;
others: papillary adenocarcinoma, 4 cases; adeno-squamous carcinoma, 4 cases; squamous cell carcinoma, 2 cases; undifferentiated carcinoma, 2 cases; neuroendocrine carcinoma, 1 case.
others: tumors other than tubular or papillary adenocarcinomas.