Table 2.
Correlation of high NNMT expression with clinical attributes in gastric cancer
Groups | NO. | NNMT | Pearson χ2 | P-value | |
---|---|---|---|---|---|
|
|||||
High no. | % | ||||
Gender | 3.832 | 0.061 | |||
Male | 464 | 246 | 53.0 | ||
Female | 153 | 95 | 62.1 | ||
Age | 1.978 | 0.161 | |||
≤60 years | 247 | 128 | 51.8 | ||
>60 years | 370 | 213 | 57.6 | ||
Histological type | 4.431 | 0.351 | |||
Tubular | 512 | 300 | 57.6 | ||
Hybrid | 7 | 3 | 42.9 | ||
Mucinous | 28 | 11 | 39.3 | ||
Signet ring cell | 21 | 11 | 52.4 | ||
Othersa | 13 | 8 | 61.5 | ||
Differentiation | 5.066 | 0.079 | |||
High | 32 | 12 | 37.5 | ||
Moderate | 157 | 87 | 55.4 | ||
Low | 383 | 222 | 58 | ||
Othersb | |||||
Primary tumor size | 33.468 | <0.001* | |||
Tis | 33 | 17 | 21.2 | ||
T1 | 62 | 28 | 45.2 | ||
T2 | 120 | 55 | 45.8 | ||
T3 | 345 | 214 | 62 | ||
T4 | 48 | 34 | 70.8 | ||
Lymph node metastasis | 33.486 | <0.001* | |||
N0 | 238 | 101 | 42.4 | ||
N1 | 108 | 60 | 55.6 | ||
N2 | 117 | 74 | 63.2 | ||
N3 | 145 | 103 | 71 | ||
Distant metastasis | 9.130 | 0.002* | |||
M0 | 580 | 312 | 53.8 | ||
M1 | 38 | 30 | 78.9 | ||
TNM stage | 46.134 | <0.001* | |||
0 | 34 | 9 | 26.5 | ||
I | 119 | 44 | 37.0 | ||
II | 200 | 112 | 56.0 | ||
III | 217 | 143 | 65.9 | ||
IV | 38 | 30 | 78.9 | ||
Preoperative CEA, ng/ml | 2.517 | 0.284 | |||
≤5 | 263 | 136 | 51.7 | ||
>5 | 74 | 44 | 59.5 | ||
Unknown | 281 | 162 | 57.7 | ||
Preoperative CA199, U/ml | 2.590 | 0.274 | |||
≤37 | 276 | 143 | 51.8 | ||
>37 | 50 | 30 | 60 | ||
Unknown | 292 | 169 | 57.9 |
P<0.05;
others: papillary adenocarcinoma, 4 cases; adeno-squamous carcinoma, 4 cases; squamous cell carcinoma, 2 cases; undifferentiated carcinoma, 2 cases; neuroendocrine carcinoma, 1 case.
others: tumors other than tubular or papillary adenocarcinomas.