Table 1.
Baseline characteristics of the patients included in the study.
| * | Total (n=242) | Compensated (n=122) | Decompensated (n=120) | p-value |
|---|---|---|---|---|
| Age | 52 (47-59) | 51 (45-59) | 53 (48-61) | 0,05 |
| Male sex (%) | 162 (67) | 80 (67) | 82 (67) | 0.963 |
| Mean BP (mmHg) | 89 (13) | 94 (13) | 85 (12) | <0.0001 |
| Heart Rate (bpm) | 76 (70-87) | 76 (70-82) | 78 (70-92) | 0.48 |
| Etiology (%) | 0.0003 | |||
| -alcohol | 64 (26) | 18 (15) | 46 (38) | |
| -viral | 120 (50) | 69 (57) | 51 (43) | |
| -others | 58 (24) | 35 (29) | 23 (19) | |
| Variceal bleeding (%) | 47 (19%) | - | 47 (39%) | - |
| Ascites (%) | 79 (33%) | - | 79 (66%) | - |
| Hepatic encephalopathy (%) | 44 (18%) | - | 44 (37%) | - |
| Jaundice (%) | 5 (2%) | - | 5 (4%) | - |
| Child Pugh Class (A/B/C) (%) (n=239) | 114/80/45 (48/33/19) | 96/21/4 (79/18/3) | 18/59/41 15/50/35) | <0.0001 |
| Child Pugh Score (n=239) | 7(5-9) | 5 (5-6) | 9 (7-11) | <0.0001 |
| MELD (n=239) | 12.1 (9.3-17.1) | 9.8 (7.9-12.1) | 15.6 (12.4-21.8) | <0.0001 |
| Bilirubin (mg/dL) (n=239) | 1.3 (0.8-2.6) | 0.9 (0.6-1.4) | 2.3 (1.1-3.9) | <0.0001 |
| Creatinine (mg/dL) (n=241) | 0.9 (0.8-1.1) | 0.9(0.7-1) | 1 (0.8-1.4) | 0.0039 |
| INR (IU) (n=239) | 1.39 (1.20-1.70) | 1.22(1.10-1.40) | 1.60(1.33-1.93) | <0.0001 |
| Albumin (g/dL) (n=239) | 3.26 (0.82) | 3.7(0.63) | 2.82 (0.76) | <0.0001 |
| AST (IU) (n=233) | 58 (36-98) | 49 (32-84) | 71 (40-115) | 0.0008 |
| ALT (IU) (n=233) | 35 (21-65) | 42 (25-75) | 30 (18-57) | 0.006 |
| Platelets (×109/L) (n=231) | 122 (83.5-173.8) | 138 (100.3-197) | 109 (69-139) | <0.0001 |
| Hemoglobin (mg/dL) (n=231) | 12.7 (2.3) | 13.9(1.7) | 11.6 (2.4) | <0.0001 |
| WBC (×103/mm3) (n=231) | 6.3 (4.6-8.3) | 5.9(4.6-7.7) | 7.0(4.7-9.8) | 0.05 |
| Liver transplant (%) | ||||
| Deaths (%) | 62 (26) | 24 (20) | 38 (32) | 0.13 |
| Follow-up (mo) | 30 (6-50) | 48 (22-54) | 14 (1-33) | <0.0001 |
Continuous variables are shown as mean(SD) or median (IQR) depending on their distribution. Some patients had more than one type of clinical decompensation. BP= blood pressure, bpm= beats per minute, MELD= Model for End-stage liver disease, WBC= white blood cells, mo= months.
*
Total number of patients with available data is specified. If there were no missing data, the total number of patients was 242.