Table 1.
Demographic and Clinical Characteristics by HIV and Hepatitis C (HCV) status
| HIV Negative |
HIV Positive |
Overall ANOVA p-value |
|||||
|---|---|---|---|---|---|---|---|
| (Mean ± SD or n (%)) | HCV Negative (n=120) |
HCV Positive (n=15) |
P- Value |
HCV Negative (n=21) |
HCV Positive (n=46) |
P- Value |
|
| Sociodemographic | |||||||
| Age (in years) | 28.4 ± 6.5 | 34.6 ± 8.6 | 0.001 | 31.0 ± 5.4 | 36.1 ± 5.2 | 0.0004 | <0.001 |
| Female | 16 (13%) | 2 (13%) | 0.99* | 5 (24%) | 2 (4%) | 0.03* | 0.11* |
| Amerindios White (1) |
22 (18%) 198 (82%) |
5 (33%) 10 (67%) |
0.18* | 9 (43%) 12 (57%) |
14 (30%) 32 (70%) |
0.41 | 0.06 |
| Recruitment Site: Cenareso Fundai |
105 (88%) 15 (13%) |
10 (67%) 5 (33%) |
0.05* |
7 (33%) 14 (67%) |
17 (37%) 29 (63%) |
0.77 | <0.001 |
| Drug, Smoking, Alcohol | |||||||
| Cigarette smoker (1) | 109 (91%) | 11 (73%) | 0.06* | 15 (71%) | 38 (84%) | 0.32* | 0.03* |
| Hazardous alcohol consumption (1,2) | 59 (50%) | 9 (60%) | 0.45 | 14 (67%) | 28 (61%) | 0.65 | 0.34 |
| In the past 6 months: (1) Injection Drug User Non-Injection Drug User Clean |
7 (6%) 104 (87%) 9 (8%) |
2 (13%) 13 (87%) 0 (0%) |
0.30* |
1 (5%) 18 (86%) 2 (10%) |
11 (24%) 28 (62%) 6 (13%) |
0.14* | 0.01* |
| Coca Paste user in past 6 mo | 87 (73%) | 11 (73%) | 0.99 | 16 (76%) | 29 (63%) | 0.29 | 0.60 |
| Dietary Intake (24 Hour Recall) | |||||||
| Total Caloric intake (kcal) | 2829.1 ± 1120.5 | 3257.2 ± 1238.2 | 0.17 | 2597.0 ± 927.6 | 2817.0 ± 929.6 | 0.37 | 0.34 |
| Fat intake (% of total kcal) | 31.7 ± 8.3 | 27.8 ± 5.4 | 0.07 | 29.5 ± 10.7 | 29.3 ± 9.7 | 0.94 | 0.17 |
| Total fat (g) | 100 ± 51 | 105 ± 57 | 0.75 | 91 ± 45 | 95 ± 46 | 0.77 | 0.77 |
| Mono-unsaturated fat (g) | 32.0 ± 17.5 | 34.5 ± 18.7 | 0.61 | 29.0 ± 15.9 | 29.7 ± 17.7 | 0.89 | 0.69 |
| Poly-unsaturated fat (g) | 18.8 ± 12.6 | 20.9 ± 17.5 | 0.57 | 15.2 ± 104 | 15.4 ± 8.4 | 0.93 | 0.20 |
| Saturated fat (g) | 36.1 ± 20.7 | 34.8 ± 15.6 | 0.82 | 34.1 ± 21.2 | 32.6 ± 20.1 | 0.78 | 0.79 |
| Cholesterol intake (mg)* | 428 ± 241 | 376 ± 209 | 0.42 | 291 ± 158 | 337 ± 233 | 0.41 | 0.02 |
| Clinical Measures | |||||||
| BMI (kg/m2) | 24.8 ± 4.2 | 23.7 ± 3.8 | 0.36 | 22.2 ± 2.4 | 23.1 ± 3.0 | 0.23 | 0.008 |
| Systolic blood pressure (mmHg) | 115 ± 9 | 115 ± 12 | 0.77 | 108 ± 12 | 112 ± 17 | 0.34 | 0.03 |
| Diastolic blood pressure(mmHg) | 71 ± 7 | 72 ± 9 | 0.71 | 69 ± 9 | 71 ± 11 | 0.56 | 0.80 |
| Laboratory | |||||||
| Total Cholesterol (mg/dL) | 176 ± 40 | 149 ± 30 | 0.01 | 155 ± 24 | 144 ± 31 | 0.16 | <0.001 |
| HDL Cholesterol (mg/dL) | 46 ± 12 | 47 ± 18 | 0.81 | 39 ± 14 | 39 ± 13 | 0.86 | 0.005 |
| LDL Cholesterol (mg/dL) | 102 ± 34 | 77 ± 25 | 0.007 | 89 ± 21 | 78 ± 24 | 0.09 | <0.001 |
| TC:HDL ratio | 4.1 ± 1.5 | 3.5 ± 1.1 | 0.12 | 4.6 ± 2.0 | 4.1 ± 1.7 | 0.29 | 0.19 |
| Triglycerides (mg/dL) | 142 ± 75 | 125 ± 68 | 0.40 | 140 ± 57 | 135 ± 61 | 0.72 | 0.79 |
| C-Reactive Protein – Reactive (3) | 24 (20%) | 3 (20%) | 0.99* | 9 (43%) | 18 (39%) | 0.77 | 0.02 |
*
Fisher’s Exact test used because 25% or more of cells had expected counts less than 5.0
(1)
Race, Alcohol, cigarette smoking, and drug use missing data for one participant.
(2)
Hazardous drinker as defined by The National Institute on Alcohol Abuse and Alcoholism. (Hazardous alcohol use definition: 7 drinks per week or 3 drinks per occasion for women and 14 drinks per week or 4 drinks per occasion in men.)
(3)
C-reactive protein was quantified by PCR-latex (Wiener Laboratory, Rosario, Argentina) which detects levels above 6 mg/l as positive.