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Plasma concentrations (±SD) of CBD in rats with and without complete Freud’s adjuvant (CFA) induction after 4 days treatment with transdermal CBD gel.
| Dose applied | Dose per unit area | CFA+CBD group (ng/mL) | All CBD treated (ng/mL) |
|---|---|---|---|
| 0.6 mg/day | 0.18 mg/cm2 | 4.3 ± 2.6 | 3.8 ± 1.4 |
| 3.1 mg/day | 0.18 mg/cm2 | 18.8 ± 2.8 | 17.5 ± 4.4 |
| 6.2 mg/day | 0.18 mg/cm2 | 34.6 ± 11.0 | 33.3 ± 9.7 |
| 62.3 mg/day | 1.8 mg/cm2 | 1470.1 ± 260.7 | 1626.9 ± 379.0 |
