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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Brain Imaging Behav. 2016 Dec;10(4):1054–1067. doi: 10.1007/s11682-015-9462-9

Figure 1.

Figure 1

Anatomy of the ventral capsule/ventral striatum (VC/VS) region targeted for DBS in OCD. Panels A and B show the topographic relationships of the caudate nucleus (Cau), putamen (Put) and globus pallidus (GP). Panel A is a gross coronal section at the level of the anterior commissure (ac), whereas B is an axial section of a high-resolution T2-MRI dataset of a postmortem human head. Panel C shows the fibers of passage connecting the thalamus with the lateral orbitofrontal (lOFC, in red) and medial orbitofrontal (mOFC, in blue) cortex at the ac coronal level in a high-resolution T2-MRI dataset of a postmortem human head. These fibers were extracted using diffusion tractography (see text). The parcellation of the orbitofrontal cortex into lateral and medial regions of interest (ROIs) was done following FreeSurfer conventions as by Desikan and colleagues (2006). In the Desikan et al. anatomical convention, lOFC ROI corresponds to the central OFC (cOFC) and lateral OFC (lOFC) ROIs of the Lehman et al. (2011) convention, whereas the mOFC ROI corresponds roughly to the ventromedial prefrontal cortex (vmPFC) and medial OFC (mOFC) ROIs of Lehman and colleagues. oc= optic chiasm.

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