Figure 6.

Photomicrographs of kidneys obtained from all groups of rats. A and B) were taken from control + vehicle and control + RES treated rats. These groups show normal architecture of kidney with prominent Bowman’s capsule, epithelial cells and normal tubules. C and D) were taken from AlCl3 intoxicated rats. The kidney sections of these rats shows mild thickening of the basement membrane along with changes in the density of mesenchyme, atrophy and degeneration of glomerular capillaries with increased Bowman’s space (urinary space) and tubular necrosis. Glomerular capillaries showed severe shrinkage and damage. Also, severe infiltration was seen (D). E and F) were taken from treated rats and shows normal architecture of glomerular capillaries, intact epithelial cells with the presence of some degeneration in the tubules and slight shrinkage of the glomerular capillaries.