Table 2. The Top 50 Hub Genes Obtained From Analysis of the Chronic HCV Network.
| Betweenness | Value | Degree | Value | Closeness | Value |
|---|---|---|---|---|---|
| JUN | 0.088456 | JUN | 60 | JUN | 0.563107 |
| KCNMA1 | 0.045263 | KCNMA1 | 38 | KCNMA1 | 0.537037 |
| SLC1A1 | 0.044697 | COL4A1 | 36 | SLC1A1 | 0.52568 |
| BCL2 | 0.035565 | SLC1A1 | 35 | LEF1 | 0.517857 |
| COL4A1 | 0.035263 | LEF1 | 33 | COL4A1 | 0.514793 |
| PODXL | 0.031336 | BCL2 | 32 | ACACB | 0.513274 |
| BIRC3 | 0.030732 | VEGFC | 31 | ENAH | 0.511765 |
| VEGFC | 0.029737 | COL1A2 | 31 | BCL2 | 0.508772 |
| WNT4 | 0.029547 | BIRC3 | 30 | VEGFC | 0.507289 |
| ENAH | 0.02707 | ENAH | 30 | COL1A2 | 0.501441 |
| POLQ | 0.026244 | SOX9 | 29 | PID1 | 0.501441 |
| ACACB | 0.025908 | COL5A1 | 29 | PODXL | 0.5 |
| LEF1 | 0.025767 | COL15A1 | 29 | WNT4 | 0.5 |
| CELF4 | 0.024233 | PODXL | 28 | BIRC3 | 0.498567 |
| FANCC | 0.022376 | WNT4 | 28 | COL15A1 | 0.497143 |
| SLCO3A1 | 0.022328 | ACACB | 28 | CELF4 | 0.494318 |
| TSPAN8 | 0.021671 | SLCO3A1 | 28 | SLCO3A1 | 0.492918 |
| SMOC2 | 0.020669 | MYOF | 28 | CD34 | 0.492918 |
| SOX9 | 0.020065 | TSPAN8 | 27 | BCAS4 | 0.491525 |
| TMEM200A | 0.019163 | SOX4 | 26 | MYOF | 0.490141 |
| SOX4 | 0.01913 | BCAS4 | 26 | TSPAN8 | 0.490141 |
| STK39 | 0.018437 | THBS2 | 26 | AGTRAP | 0.490141 |
| COL5A1 | 0.017963 | CD44 | 26 | BRCA1 | 0.488764 |
| CBLN1 | 0.017321 | CELF4 | 25 | KCNN2 | 0.487395 |
| ADCY1 | 0.016641 | PID1 | 25 | SOX9 | 0.486034 |
| OSBPL3 | 0.016441 | COL4A2 | 25 | SOX4 | 0.486034 |
| BCAS4 | 0.01626 | ADRA1A | 24 | SPP1 | 0.486034 |
| MYOF | 0.015722 | CD34 | 24 | STK39 | 0.483333 |
| COL1A2 | 0.014797 | STK39 | 23 | COL5A1 | 0.481994 |
| THBS2 | 0.014385 | BRCA1 | 23 | PDGFRB | 0.481994 |
| CCL20 | 0.014217 | SPP1 | 23 | FRZB | 0.481994 |
| TGFBI | 0.014096 | CHRM3 | 23 | CHRM3 | 0.480663 |
| FRZB | 0.014042 | KCNN2 | 23 | SMOC2 | 0.480663 |
| COL15A1 | 0.014024 | POLQ | 22 | CBLN1 | 0.480663 |
| CD44 | 0.013973 | FANCC | 22 | ERBB2 | 0.479339 |
| FST | 0.013728 | SMOC2 | 22 | THBS2 | 0.476712 |
| STAG3 | 0.01337 | TMEM200A | 22 | ADRA1A | 0.476712 |
| S100A13 | 0.013157 | CBLN1 | 22 | POLQ | 0.476712 |
| ACSL1 | 0.012823 | TGFBI | 22 | VWF | 0.476712 |
| DACT2 | 0.012597 | ST3GAL6 | 22 | PARM1 | 0.476712 |
| BRCA1 | 0.01237 | COL1A1 | 22 | NOS1AP | 0.476712 |
| RRM2 | 0.012267 | OSBPL3 | 21 | ST3GAL6 | 0.47541 |
| ADRA1A | 0.012258 | PDGFRB | 21 | COL1A1 | 0.47541 |
| PLVAP | 0.011888 | B3GALNT1 | 20 | CMIP | 0.47541 |
| SPP1 | 0.011585 | ERBB2 | 20 | TGFBI | 0.472826 |
| B3GALNT1 | 0.011486 | AGTRAP | 20 | TMEM200A | 0.471545 |
| SFRP5 | 0.011395 | ADCY1 | 19 | ASPH | 0.47027 |
| CHRM3 | 0.011097 | STAG3 | 19 | CD44 | 0.469003 |
| KCNN2 | 0.01109 | DCDC2 | 19 | SERPINE2 | 0.469003 |
| PID1 | 0.011078 | VWF | 19 | COL4A2 | 0.467742 |