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. 2016 Feb 20;16(2):e36005. doi: 10.5812/hepatmon.36005

Table 2. The Top 50 Hub Genes Obtained From Analysis of the Chronic HCV Network.

Betweenness Value Degree Value Closeness Value
JUN 0.088456 JUN 60 JUN 0.563107
KCNMA1 0.045263 KCNMA1 38 KCNMA1 0.537037
SLC1A1 0.044697 COL4A1 36 SLC1A1 0.52568
BCL2 0.035565 SLC1A1 35 LEF1 0.517857
COL4A1 0.035263 LEF1 33 COL4A1 0.514793
PODXL 0.031336 BCL2 32 ACACB 0.513274
BIRC3 0.030732 VEGFC 31 ENAH 0.511765
VEGFC 0.029737 COL1A2 31 BCL2 0.508772
WNT4 0.029547 BIRC3 30 VEGFC 0.507289
ENAH 0.02707 ENAH 30 COL1A2 0.501441
POLQ 0.026244 SOX9 29 PID1 0.501441
ACACB 0.025908 COL5A1 29 PODXL 0.5
LEF1 0.025767 COL15A1 29 WNT4 0.5
CELF4 0.024233 PODXL 28 BIRC3 0.498567
FANCC 0.022376 WNT4 28 COL15A1 0.497143
SLCO3A1 0.022328 ACACB 28 CELF4 0.494318
TSPAN8 0.021671 SLCO3A1 28 SLCO3A1 0.492918
SMOC2 0.020669 MYOF 28 CD34 0.492918
SOX9 0.020065 TSPAN8 27 BCAS4 0.491525
TMEM200A 0.019163 SOX4 26 MYOF 0.490141
SOX4 0.01913 BCAS4 26 TSPAN8 0.490141
STK39 0.018437 THBS2 26 AGTRAP 0.490141
COL5A1 0.017963 CD44 26 BRCA1 0.488764
CBLN1 0.017321 CELF4 25 KCNN2 0.487395
ADCY1 0.016641 PID1 25 SOX9 0.486034
OSBPL3 0.016441 COL4A2 25 SOX4 0.486034
BCAS4 0.01626 ADRA1A 24 SPP1 0.486034
MYOF 0.015722 CD34 24 STK39 0.483333
COL1A2 0.014797 STK39 23 COL5A1 0.481994
THBS2 0.014385 BRCA1 23 PDGFRB 0.481994
CCL20 0.014217 SPP1 23 FRZB 0.481994
TGFBI 0.014096 CHRM3 23 CHRM3 0.480663
FRZB 0.014042 KCNN2 23 SMOC2 0.480663
COL15A1 0.014024 POLQ 22 CBLN1 0.480663
CD44 0.013973 FANCC 22 ERBB2 0.479339
FST 0.013728 SMOC2 22 THBS2 0.476712
STAG3 0.01337 TMEM200A 22 ADRA1A 0.476712
S100A13 0.013157 CBLN1 22 POLQ 0.476712
ACSL1 0.012823 TGFBI 22 VWF 0.476712
DACT2 0.012597 ST3GAL6 22 PARM1 0.476712
BRCA1 0.01237 COL1A1 22 NOS1AP 0.476712
RRM2 0.012267 OSBPL3 21 ST3GAL6 0.47541
ADRA1A 0.012258 PDGFRB 21 COL1A1 0.47541
PLVAP 0.011888 B3GALNT1 20 CMIP 0.47541
SPP1 0.011585 ERBB2 20 TGFBI 0.472826
B3GALNT1 0.011486 AGTRAP 20 TMEM200A 0.471545
SFRP5 0.011395 ADCY1 19 ASPH 0.47027
CHRM3 0.011097 STAG3 19 CD44 0.469003
KCNN2 0.01109 DCDC2 19 SERPINE2 0.469003
PID1 0.011078 VWF 19 COL4A2 0.467742