Table 2.
Prevalence of Pfdhfr/Pfdhps haplotypes.
| Haplotypes: Pfdhfr/Pfdhps | 2005 | 2008 | p | ||
|---|---|---|---|---|---|
| n | % | n | % | ||
| 108N-59C/R∗-51I-437G (NC/RIG) | 0/29 | 0 | 2/55 | 3.6 | NS |
| 108N-59R-51I-437A/G∗ (NRIA/G) | 1/29 | 3.4 | 0/55 | 0 | NS |
| 108N-59R-51I-A437 (NRIA) | 15/29 | 51.7 | 16/55 | 29.9 | 0.04 |
| 108S-59R-51I-437G (SRIG) | 0/29 | 0 | 1/55 | 1.8 | NS |
| Quadruple mutation: 108N-59R-51I-437G | 10/29 | 34.4 | 35/55 | 64.8 | 0.01 |
∗Parasites carrying mixed infections designated by two genotypes at the codon indicated above. NS: not significant. For the calculation of the haplotype frequencies, samples with both dhfr and dhps genes analysis have been selected.