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NHE super family. The plasma membrane and intracellular organelle clusters of NHE isoforms are illustrated: NHE members 1–5 are located in the plasma membrane (yellow) and the NHE members 6–9 are located in the intracellular organelles (blue). Red font denotes the isoforms which have been discussed in detail in this review. Canonical sequence alignment was performed using ClustalX and the tree was constructed using FigTree (Thompson et al., 1997).
