Table 2.
Logistic Regression Results | Cumulative Incidence Results | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Overall | C | I | 5-Year | 10-Year | |||||||||||
Late Effect | N | % | N | % | N | % | OR (95% CI) | p- value |
Total | C | I | C | I | HR* | p- value |
Ischemic and Thrombotic Events |
153 | 24 | 64 | 20 | 89 | 27 | 0.69 (0.47–0.99) | .05 | 30 | 16 | 23 | 24 | 33 | 0.69 | .02 |
Acute MI | 51 | 8 | 23 | 7 | 28 | 9 | 0.82 (0.46–1.47) | .51 | 10 | 5 | 6 | 8 | 10 | 0.80 | .42 |
Ischemic Heart Disease |
49 | 8 | 18 | 6 | 31 | 10 | 0.56 (0.31–1.03) | .06 | 9 | 5 | 8 | 7 | 12 | 0.55 | .05 |
Thrombosis (severe) | 85 | 13 | 37 | 12 | 48 | 15 | 0.79 (0.5–1.26) | .33 | 17 | 9 | 12 | 14 | 17 | 0.79 | .28 |
Endocrine | 273 | 43 | 138 | 44 | 135 | 41 | 1.15 (0.83–1.59) | .39 | 52 | 44 | 41 | 51 | 48 | 1.06 | .69 |
Diabetes | 123 | 19 | 62 | 20 | 61 | 19 | 1.12 (0.75–1.67) | .58 | 24 | 19 | 18 | 23 | 22 | 1.08 | .69 |
Diabetes with Sequelae |
56 | 9 | 26 | 8 | 30 | 9 | 0.9 (0.52–1.57) | .72 | 12 | 8 | 8 | 9 | 10 | 0.89 | .66 |
Hypercholesterolemia | 200 | 31 | 99 | 32 | 101 | 31 | 1.04 (0.74–1.45) | .83 | 39 | 30 | 29 | 37 | 37 | 1.00 | 1.00 |
Obesity | 42 | 7 | 25 | 8 | 17 | 5 | 1.59 (0.83–3.01) | .16 | 8 | 7 | 5 | 9 | 6 | 1.49 | .20 |
Osteoporosis | 135 | 21 | 73 | 23 | 62 | 19 | 1.29 (0.87–1.9) | .20 | 26 | 21 | 18 | 27 | 22 | 1.17 | .35 |
Fracture | 99 | 15 | 53 | 17 | 46 | 14 | 1.24 (0.8–1.92) | .34 | 19 | 12 | 10 | 20 | 17 | 1.17 | .43 |
All Bone | 182 | 28 | 97 | 31 | 85 | 26 | 1.28 (0.9–1.82) | .17 | 35 | 27 | 23 | 36 | 31 | 1.16 | .32 |
SEXUAL DYSFUNCTION |
|||||||||||||||
Organic | 36 | 6 | 20 | 6 | 16 | 5 | 1.32 (0.67–2.61) | .42 | 7 | 6 | 5 | 8 | 6 | 1.29 | .46 |
MISCELLANEOUS | |||||||||||||||
Dementia | 33 | 5 | 22 | 7 | 11 | 3 | 2.05 (0.97–4.36) | .06 | 7 | 5 | 2 | 8 | 4 | 1.97 | .07 |
Depression | 89 | 14 | 43 | 14 | 46 | 14 | 0.94 (0.59–1.47) | .77 | 18 | 11 | 12 | 15 | 16 | 0.92 | .69 |
Acute Kidney Injury | 122 | 19 | 60 | 19 | 62 | 19 | 1.02 (0.68–1.52) | .93 | 30 | 14 | 14 | 21 | 21 | 0.98 | .91 |
Regression analyses were conducted separately for each adverse event type in multivariable regression models, adjusting for demographic and stratification factors as covariates as specified in the Methods.
Represents the subdistribution hazard ratios based on competing risk regression analyses.