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. Author manuscript; available in PMC: 2016 May 2.
Published in final edited form as: Nature. 2015 Oct 7;526(7573):435–438. doi: 10.1038/nature14979

Figure 3. Firing rates of identified vM GABAergic neurons across brain states.

Figure 3

a, Example recording of spontaneous and laser-evoked spikes from a vM neuron. Blue ticks, laser pulses (30 Hz). b, Comparison between laser-evoked (blue) and averaged spontaneous (red) spike waveforms from this unit. c, Spike raster showing multiple trials of laser stimulation at 15 and 30 Hz. d, Firing rates of an example vM GABAergic neuron. e, Left, mean firing rates of the neuron in (d) during different brain states. Error bar, ±s.e.m. Right, firing rates of the neuron during different wakeful behaviors. f, Firing rates of 20 identified vM GABAergic neurons during different brain states. Each line shows firing rates of one unit; gray bar, average across units. g, Relative firing rates across brain states. The rates of each neuron were normalized by its maximum. All 20 neurons showed maximum firing rates during REM sleep (the difference was significant at P<0.005 for all 20 neurons compared to NREM and wakefulness; Wilcoxon rank sum test, post-hoc Bonferroni correction). h, Relative firing rates of 17 vM GABAergic neurons during different wakeful behaviors.

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