Table 4.

SNP heritability (h²_SNP) of HRSD items (full sample, N=1558)

Model	N	h2SNP	(SE)	P
No Covariates
Initial Insomnia	1558	0.22	0.12	<0.01
Middle Insomnia	1558	0.06	0.11	0.19
Delayed Insomnia	1558	0.18	0.12	<0.01
Depressed Mood	1558	0.04	0.09	0.27
Guilt	1558	0.06	0.09	0.10
Suicide	1558	0.03	0.05	0.21
Work and Interest	1558	0.36	0.14	<0.01
Somatic Energy	1558	0.20	0.16	0.16
Psychomotor Retardation	1558	0.53	0.15	<0.01
Psychological Anxiety	1558	0.34	0.16	0.01
Somatic Anxiety	1558	0.02	0.07	0.40
Hypochondriasis	1558	0.12	0.07	<0.01
Psychomotor Agitation	1558	0.10	0.13	0.17
Appetite	1558	0.43	0.16	0.01
Weight Loss	1558	0.10	0.13	0.13
Insight	1558	0.06	0.09	0.10
Libido	1558	0.29	0.16	0.06
Age, Gender, APCs as covariates
Initial Insomnia	1558	0.13	0.16	0.17
Middle Insomnia	1558	0.06	0.15	0.32
Delayed Insomnia	1558	<0.01	0.15	0.50
Depressed Mood	1558	0.05	0.18	0.41
Guilt	1558	<0.01	0.17	0.50
Suicide	1558	<0.01	0.17	0.50
Work and Interest	1558	0.29	0.16	0.03
Somatic Energy	1558	0.27	0.17	0.05
Psychomotor Retardation	1558	0.57	0.16	<0.01
Psychological Anxiety	1558	0.37	0.17	0.01
Somatic Anxiety	1558	<0.01	0.16	0.50
Hypochondriasis	1558	<0.01	0.17	0.50
Psychomotor Agitation	1558	0.12	0.16	0.22
Appetite	1558	0.49	0.16	<0.01
Weight Loss	1558	0.12	0.16	0.22
Insight	1558	<0.01	0.17	0.50
Libido	1558	0.36	0.17	0.02

Abbreviations: P - p-value form the one-tailed t-tests; SE - standard error of the estimate