Fig. 3.

Deletion of SPI-13 but not SPI-14 results in impaired colonization of the cecum (a), reduced invasion of the intestinal epithelium (b), and impaired colonization of the liver (c) and spleen (d). Bars represent mean ± SEM of three mice for each time point except for day 7 p.i. where in the ΔSPI-13/14 infected group where mean intracellular cecal counts from two animals were used. Significant differences were determined using a one-way ANOVA with Tukey’s post hoc for multiple comparisons (*P < 0.05)