A. Major criteria (both criteria required) |
1. Severe fatigue >6 months |
a. Persistent or relapsing in course |
b. Does not resolve with bed rest |
c. Significant reduction in average daily activity (below 50 % of prior activity) |
2. Other causes excluded |
a. See fatigue causes |
B. Minor criteria (4 or more present for 6 months) |
1. Headache |
a. New type, severity or pattern |
b. Typically non-focal headache |
2. Migratory polyarthralgias |
a. Non-inflammatory (no swelling or erythema) |
3. Myalgias |
4. Postexertional malaise or fatigue |
a. Duration >24 h |
5. Short-term memory or concentration impaired |
6. Pharyngitis |
7. Tender cervical or axillary adenopathy |
8. Non-restorative sleep |