Table 3.
Characteristics of individuals enrolled in this study
| c.709-1G > A mutation carriers | |||
|---|---|---|---|
| Control n = 10 | Asymptomatic n = 12 | FTLD patients n = 7 | |
| Age (years) | 51.8 ± 4.3 | 52.8 ± 4.3 | 65.3 ± 2.3 |
| Sex, female, % (n) | 50 % (5) | 50 % (6) | 100 % (7) |
| Age at onset | - | - | 61 ± 0.6 |
| Phenotype | Asymptomatic | Asymptomatic | FTD-bv; CBS |
| Family history, % (n) | 70 % (7) | 54.5 % (6) | 57.1 % (4) |
Control: Individuals without sing of neurological degeneration; c.709-1G > A: GRN mutation carriers; n: number of subjects. Values are expressed as mean ± SEM. CBS Cortico-basal syndrome, FTD-bv Frontotemporal dementia (behavior)