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. 2016 Apr 13;6(4):150231. doi: 10.1098/rsob.150231

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© 2016 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 5. — Relish is regulated by EGFR/AKT/ERK signalling pathway. (a) The protein level of Relish in avermectin-susceptible (S) larvae treated with different concentrations of lapatinib (Lap), wortmanin (Wort) or U0126 for 48 h. (b–d) The protein level of Relish in larvae treated with avermectin (AVM) plus lapatinib (b), wortmanin (c) or U0126 (d) for 48 h. (e) The protein level of Relish in S2 cells treated with different concentrations of AVM for 1 h; or pretreated with lapatinib, wortmanin or U0126 for 2 h and then treated with 1 µM AVM for 1 h.