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. 2016 Apr 27;6(4):160009. doi: 10.1098/rsob.160009

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© 2016 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 5. — Location of the NLR genes in the genome in assemblies Zv9 and GRCz10. (a) The chromosomes containing NLR-B30.2 genes are shown in the outer circle (note that corrections of the genome between Zv9 and the GRCz10 have changed the lengths of some of the chromosomes. The genes were annotated on Zv9 and lifted over to the GRCz10 path where possible as the GRCz10 gene set did not become available until May 2015. The members of the four groups of NLR genes are shown as radial lines within the circles with group 1 in the outermost and group 4 in the inner ring. Each gene is connected by a black line to its most closely related paralogue, based on the number of amino acid substitutions per site calculated in MEGA5 (Poisson correction model). Most genes are most closely related to a near neighbour, resulting in a line reaching towards the centre and returning to nearly its origin (for example, the group 2 genes on chromosome 22). The changes in the assembly have led to many genes that were closely related but resided on different chromosomes in Zv9 being located in closer proximity in GRCz10. (b) Normalized location of NLR-B30.2 genes on chromosomes. Each chromosome is shown as a horizontal line of 100% length, and the NLR genes are plotted at their relative positions along the chromosome. Apart from the genes on chromosome 4 (marked in blue), all other genes are found within the first or last quarter of the chromosome.