Table 1.
Demographic and Clinical Characteristics (n=13)
| Mean ± S.E.M. | Percent | |
|---|---|---|
| Age (years) | 46.6 ± 2.6 | |
| BMI (kg/m2) | 29.6 ± 1.3 | |
| Age at first major depressive episode (years) | 26.6 ± 3.0 | |
| Duration of illness (years) | 18.9 ± 2.5 | |
| Duration of index episode (years) | 10.7 ± 2.0 | |
| Number of adequate antidepressant trials | 5.5 ± 0.7 | |
| MADRS pre-treatment | 33.6 ± 1.4 | |
| MADRS post-treatment | 12.8 ± 2.6 | |
| Response rate | 77% | |
| Male | 61% | |
| White | 85% | |
| Hispanic ethnicity | 23% | |
| Right-handed | 85% | |
| History of psychiatric hospitalization | 46% | |
| Melancholic depression | 61% | |
| History of suicide attempts | 23% | |
| History of alcohol abuse/dependence | 31% | |
| History of substance abuse/dependence | 15% |
Abbreviations: BMI, Body Mass Index; MADRS, Montgomery-Åsberg Depression Rating Scale.