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. 2016 Apr 18;7:11337. doi: 10.1038/ncomms11337

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(a) Stereoviews of CaMep2 showing 2F_o–F_c electron density (contoured at 1.0 σ) for CTR residues Asp419-Met422 and for Tyr446-Thr455 of the AI region. For clarity, the residues shown are coloured white, with oxygen atoms in red and nitrogen atoms in blue. The phosphorylation target residue Ser453 is labelled in bold. (b) Overlay of the CTRs of ScMep2 (grey) and CaMep2 (green), showing the similar electronegative environment surrounding the phosphorylation site (P). The AI regions are coloured magenta. (c) Cytoplasmic view of the Mep2 trimer indicating the large distance between Ser453 and the channel exits (circles; Ile52 lining the channel exit is shown).