Figure 3.
Western blotting analysis of the NLRP3 and caspase-1 p20 expression in muscle tissue (mean ± SD, n = 3–6). The relative grayscale of NLRP3 and p20 was significantly higher in the DM/PM group than that in the control group and no significant difference between the DM and PM groups (Western blotting analysis of NLRP3, DM vs. control *P < 0.01, PM vs. control †P < 0.01; Western blotting analysis of p20, DM vs. control ‡P < 0.01, PM vs. control §P < 0.01). DM: Dermatomyositis; PM: Polymyositis; GAPDH: Glyceraldehyde-3-phosphate dehydrogenase; NLRP3: NOD-like receptor family, pyrin domain containing 3 inflammasome; SD: Standard deviation.