Table 1.

Characteristics of 26 patients diagnosed with TM from September 2005 to April 2014 in Fujian, China

Characteristics	HIV-negative (n = 7)	HIV-positive (n = 19)	Statistical values	P
Age (years)	44 ± 25	42 ± 12	0.17*	0.867
Weight (kg)¶	54 ± 25	57 ± 6	5.27†	0.751
Duration from symptom onset to diagnosis (days)	60 (20, 180)	30 (10, 45)	31.50†	0.041
Male	6 (86)	15 (79)	0.15‡	0.999
Employment	1 (15)	1 (6)	2.53‡	0.474
Smoking	2 (29)	7 (37)	0.16‡	0.999
Drinking	1 (14)	3 (16)	0.01‡	0.999
Underlying diseases§,||	5 (71)	11 (58)	0.40‡	0.668
Malignancy	1 (14)	0	2.82‡	0.269
Systemic lupus erythematosus	2 (29)	0	5.88‡	0.065
Primary immunodeficiency	1 (14)	0	2.82‡	0.269
Leukemia	1 (14)	0	2.82‡	0.269
Opportunistic infection¶	1 (17)	14 (74)	6.18‡	0.023
Fungus††	1	9		–
Herpes††	0	3		–
Syphilis††	0	3		–
Hepatitis B virus††	0	1		–
Heart disease	0	1 (5)	0.38‡	0.999
Liver dysfunction**	2 (29)	10 (59)	1.82‡	0.371
Hepatitis B	0	1 (5)	0.38‡	0.999
Multiple organ dysfunction syndrome	0	1 (5)	0.38‡	0.999

Age and weight are presented as mean ± SD, disease duration as median (P₂₅, P₇₅), and other parameters as count (%). P values were estimated by an *Independent t-test, ^†Mann–Whitney U-test, or ^‡Fisher’s exact test;^§Underlying disease indicates malignancy, systemic lupus erythematosus, primary immunodeficiency and any disease of the heart, liver or kidney;^|| One patient may have more than one underlying disease; ^¶Missing data were found in six patients for weight and in one patient for opportunistic infection; **Liver dysfunction was defined as aminotransferase >40 U/L and aspartate aminotransferase >40 U/L; ^††One patient might be infected by two or more pathogens. Dash indicates no comparisons were done. SD: Standard deviation; TM: Talaromyces marneffei; HIV: Human immunodeficiency virus.