Table 3.
Biochemical indexes of 26 patients diagnosed with Penicilliosis marneffei in Fujian, China
| Biochemical index | HIV-negative (n = 7) | HIV-positive (n = 19) | U† | P |
|---|---|---|---|---|
| WBC (109/L), median (IQR)* | 9 (3–12) | 4 (3–6) | 43.00 | 0.178 |
| <4×109/L , n (%) | 2 (29) | 9 (50) | 0.252 | |
| (4–10)×109/L, n (%) | 3 (42) | 8 (44) | ||
| >10×109/L, n (%) | 2 (29) | 1 (6) | ||
| Hemoglobin (g/L), median (IQR)§ | 110.0 (95.0–150.0) | 106.0 (89.0–118.0) | 54.00 | 0.497 |
| Normal, n (%) | 3 (43) | 5 (26) | 0.671 | |
| Mild anemia, n (%) | 3 (43) | 9 (48) | ||
| Severe anemia, n (%) | 1 (14) | 5 (26) | ||
| Platelets (109/L), median (IQR) | 147.0 (95.0–201.0) | 113.0 (80.0–151.0) | 48.00 | 0.306 |
| <100×109/L, n (%) | 2 (29) | 6 (32) | 0.243 | |
| 100–300×109/L, n (%) | 4 (57) | 13 (68) | ||
| >300×109/L, n (%) | 1 (14) | 0 | ||
| Albumin (g/L), median (IQR)|| | 30 (27–35) | 29 (21–31) | 43.50 | 0.244 |
| <30 g/L, n (%) | 4 (57) | 8 (44) | 0.673 | |
| ≥30 g/L, n (%) | 3 (43) | 10 (56) | ||
| ALT (U/L), median (IQR) | 38 (16–48) | 48 (33–70) | 35.70 | 0.130 |
| AST (U/L), median (IQR) | 36.0 (27.0–133.0) | 70.0 (56.0–141.0) | 37.50 | 0.125 |
| Neutrophils (%), median (IQR) | 71 (45–80) | 82 (73–91) | 27.00 | 0.029 |
| ALP (U/L), median (IQR) | 93.0 (52.0–120.0) | 90.0 (75.0–148.0) | 51.00 | 0.901 |
| Total bilirubin (μmol/L), median (IQR) | 9 (7–12) | 9 (7–11) | 57.00 | 0.874 |
| CD4 (%), median (IQR)|| | 41 (35–46) | 2 (1–3) | 0.00 | 0.009 |
| C3 (g/L), median (IQR)|| | 1 (0–1) | 1 (0–1) | 19.50 | 0.941 |
| Lymphocytes (%), median (IQR) | 21 (15–42) | 12 (7–19) | 21.00 | 0.009 |
| Lymphocyte (109/L), median (IQR) | 2 (1–4) | 0 (0–1) | 20.00 | 0.008 |
*Data were not available for one patient for WBC and albumin, ten patients for CD4, and 13 patients for C3. †Mann–Whitney U-test §Hemoglobin was defined as normal (>120 g/L), mild anemia (90–120 g/L for males and 90–110 g/L for females), or moderate anemia (60–90 g/L); ||Data were not available for one patient for WBC and albumin, ten patients for CD4, and 13 patients for C3. IQR: Interquartile range; ALT: Alanine aminotransferase; AST: Aspartate transaminase; ALP: Alkaline phosphatase; WBC: White blood cells; HIV: Human immunodeficiency virus.