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. 2016 May 5;129(9):1078–1086. doi: 10.4103/0366-6999.180527

Table 4.

ROC curves of sphingolipid biomarker levels for predicting MACE in young patients after discharge

Marker Cut-off value Sensitivity (%) Specificity (%) AUC P 95% CI*
AY group
 Cer(d18:0/16:0) 1,385,000 100.00 42.11 0.671 0.292 0.411–0.931
 Cer(t18:0/12:0) 465,214 75.00 78.95 0.750 0.123 0.421–1.079
 Sphinganine 8,950,000 75.00 73.68 0.711 0.194 0.474–0.947
SY group
 Cer(d18:0/16:0) 1,170,000 100.00 66.67 0.778 0.089 0.589–0.967
 Cer(t18:0/12:0) 462,514 100.00 72.22 0.833 0.041 0.654–1.103
 Sphinganine 7,430,000 100.00 66.67 0.806 0.061 0.622–0.989

*Null hypothesis: True area: 0.5. CI: Confidence interval; ROC: Receiver operating characteristic; MACE: Major adverse cardiovascular events; AUC: Area under curve; Cer: Ceramide.