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. Author manuscript; available in PMC: 2016 May 2.
Published in final edited form as: Microcirculation. 2013 Feb;20(2):158–169. doi: 10.1111/micc.12014

Figure 4.

Figure 4

In vitro responses to endothelium-dependent dilators in coronary and mesenteric arterioles. (A) Panel (1): Coronary arteriolar dose-dependent dilation to A23187 was inhibited following pulmonary exposure to PMMTM. Panel (2): Similarly, mesenteric arteriolar dilation induced by A23187 was also inhibited following PMMTM exposure. (B) Panel (1): ACh (a muscarinic receptor agonist) induced dilation coronary arterioles in sham-treated animals, but not in PMMTM-exposed. Panel (2) Mesenteric arteriolar dilation was significantly inhibited following PMMTM instillation compared with sham-treated animals. *p < 0.05 vs. sham.