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Vessel characteristics
| Sham |
MTM |
|||||
|---|---|---|---|---|---|---|
| n | Diameter (μm) | Tone (%) | n | Diameter | Tone | |
| Intravital microscopy | ||||||
| Normal | 44 | 36 ± 1 | 64 ± 1 | 29 | 38 ± 2 | 63 ± 2 |
| l-NMMA | 13 | 39 ± 2 | 61 ± 3 | 10 | 36 ± 2 | 69 ± 2* |
| Phentolamine | 9 | 35 ± 3 | 66 ± 3 | 8 | 37 ± 6 | 65 ± 6 |
| ADO | 45 | 103 ± 3 | 0 | 32 | 106 ± 3 | 0 |
| Isolated arterioles | ||||||
| Mesenteric | 16 | 70 ± 4 | 30 ± 2 | 10 | 78 ± 3 | 25 ± 2 |
| Ca++ free | 99 ± 3 | 0 | 104 ± 2 | 0 | ||
| Coronary | 18 | 88 ± 4 | 24 ± 8 | 16 | 95 ± 8 | 30 ± 3 |
| Ca++ free | 116 ± 20 | 0 | 135 ± 10 | 0 | ||
p < 0.05 vs. sham.
