Table 10.
The position and affinity of neuraminidase epitope H5N1-bound class I and class II HLA.
| POSITION | EPITOPE | ALLELE | HYDROGEN BONDING | ΔGBINDING (kcal/mol) |
|---|---|---|---|---|
| 2 | NPNQKIITI | HLA B*0702 | Asp 114, Arg 156, Tyr 159, Glu 163, Val 165, Arg 169, Arg 170 | −23.8779 |
| 188 | YNGIITDTI | HLA DRB1-0101 | Glu 28, Arg 71, Arg 72, Val 75, Thr 77, Cys 79, dan Asn 82 | −17.8049 |
| 261 | CYPDAGEIT | HLA A*24 | Lys 12, Asp 74, Tyr 85, Tyr 123, Asp 137, Met 138, dan Ala 139 | −33.0200 |
| 398 | IRPCFWVEL | HLA B*2705 | Asp 77, Tyr 84, His 93, Thr 94, Gln 96, Asp 119, dan Thr 143 | −33.6376 |
| 399 | RPCFWVELI | HLA B*0702 | Tyr 7, Tyr 159, Tyr 9, Tyr 99, Arg 62, Glu 152, dan Gln 155 | −24.8928 |