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. 2016 May 2;11(5):e0154555. doi: 10.1371/journal.pone.0154555

Table 5. Genes up- or down-regulated in common by nsEP exposure in Jurkat and U937 cells.

Gene Symbol Gene name Jurkat Fold Change p-Value U937 Fold Change p-Value
JUN jun proto-oncogene 3.606 0.0026 2.444 0.0001
VEGFA vascular endothelial growth factor A 2.594 0.0396 1.32 0.0146
RORA RAR-related orphan receptor A 2.569 0.0471 1.949 0.0072
MXD1 MAX dimerization protein 1 2.354 0.0095 1.635 0.0072
ATF3 activating transcription factor 3 2.301 0.0005 1.216 0.0014
PPP1R15A protein phosphatase 1, regulatory subunit 15A 2.298 0.0032 2.21 0.0002
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha, 10, 42kDa 2.286 0.0018 1.83 0.0424
BHLHE40 basic helix-loop-helix family, member e40 2.235 0.0338 1.253 0.0013
LDLR low density lipoprotein receptor 2.218 0.0096 2.463 0.0386
NRP2 neuropilin 2 2.082 0.0295 3.022 0.0031
SASH1 SAM and SH3 domain containing 1 2.081 0.0000 1.768 0.0204
TBX3 T-box 3 2.024 0.0420 2.052 0.0060
DOCK4 dedicator of cytokinesis 4 1.942 0.0134 1.307 0.0303
SLC7A11 solute carrier family 7 member 11 1.875 0.0041 2.309 0.0040
ULK2 unc-51 like autophagy activating kinase 2 1.848 0.0293 1.38 0.0177
S1PR3 sphingosine-1-phosphate receptor 3 1.824 0.0463 1.18 0.0047
DUSP10 dual specificity phosphatase 10 1.821 0.0046 1.571 0.0108
CHD2 chromodomain helicase DNA binding protein 2 1.75 0.0034 1.511 0.0231
TSC22D3 TSC22 domain family, member 3 1.729 0.0370 1.807 0.0408
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 1.718 0.0290 2.412 0.0409
EYA3 EYA transcriptional coactivator and phosphatase 3 1.613 0.0322 2.8 0.0480
RNA45S5 RNA, 45S pre-ribosomal 5 1.599 0.0003 2.887 0.0009
CREBRF CREB3 regulatory factor 1.578 0.0267 1.092 0.0232
RNF31 ring finger protein 31 1.545 0.0488 1.72 0.0123
CAMK2B calcium/calmodulin-dependent protein kinase II beta 1.529 0.0252 1.706 0.0387
KLF6 Kruppel-like factor 6 1.473 0.0016 1.939 0.0029
SESN2 sestrin 2 1.463 0.0123 1.606 0.0000
MASP2 mannan-binding lectin serine peptidase 2 1.448 0.0179 2.265 0.0283
ARG1 arginase 1 1.382 0.0441 1.386 0.0430
NPR1 natriuretic peptide receptor 1 1.362 0.0080 2.291 0.0118
TM4SF1 transmembrane 4 L six family member 1 1.349 0.0249 4.417 0.0195
FAM122C family with sequence similarity 122C 1.31 0.0341 1.058 0.0162
JUND jun D proto-oncogene 1.308 0.0042 1.733 0.0057
SPATA6 spermatogenesis associated 6 1.27 0.0237 1.924 0.0105
PHLDA1 pleckstrin homology-like domain, family A, member 1 1.142 0.0074 2.861 0.0002
NEU1 sialidase 1 (lysosomal sialidase) 1.134 0.0296 1.201 0.0014
CD55 CD55 molecule, decay accelerating factor for complement 1.11 0.0324 1.321 0.0062
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 1.079 0.0455 1.267 0.0052
SKIL SKI-like proto-oncogene 1.073 0.0026 1.554 0.0302
HAO2 hydroxyacid oxidase 2 (long chain) 1.042 0.0494 1.618 0.0393
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene F 1.007 0.0170 1.653 0.0022
MEX3D mex-3 RNA binding family member D -1.045 0.0318 -2.098 0.0012
EBF3 early B-cell factor 3 -1.082 0.0122 -1.047 0.0403
ZNF205 zinc finger protein 205 -1.083 0.0039 -2.33 0.0060
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 -1.123 0.0417 -2.111 0.0041
XIRP2 xin actin-binding repeat containing 2 -1.19 0.0204 -2.27 0.0255
TEX14 testis expressed 14 -1.22 0.0002 -1.113 0.0242
CLECL1 C-type lectin-like 1 -1.23 0.0407 -2.337 0.0097
HNRNPD heterogeneous nuclear ribonucleoprotein D -1.307 0.0083 -1.545 0.0113
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 -1.32 0.0411 -1.784 0.0319
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -1.38 0.0121 -1.722 0.0199
GPR98 G protein-coupled receptor 98 -1.515 0.0408 -1.46 0.0232
SATB1 SATB homeobox 1 -1.97 0.0350 -1.548 0.0003
RERE arginine-glutamic acid dipeptide (RE) repeats -2.105 0.0373 -2.224 0.0488
FERMT1 fermitin family member 1 -2.548 0.0123 -1.4 0.0182
TSEN54 TSEN54 tRNA splicing endonuclease subunit -2.707 0.0058 -1.638 0.0389
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -2.862 0.0066 -1.037 0.0132
HAPLN1 hyaluronan and proteoglycan link protein 1 -3.471 0.0045 -2.922 0.0221