Table 3. Software predicted candidate Dlk1-Dio3 mat miRNA target genes.

	Ontology Predicted Targets
miR-127	TGF-ßR1
miR-136	CD28, Fas-L, PI3K
miR-376c	CXCL1, 5, 16, IFNa6, IL-1RAP, IL-2, PDGFRa, ß, PI3K, Smad4, Smurf1, TGF-ßR1, TNFSF4
miR-379	AMPK, Bcl-2, Collagen IV, HGF, IGF1, IGF1R, PDGF, PG-F2R, PTEN, Smad4, Smurf1, SREBP1, TGF-ßR1
miR-409-3p	AMPK, Collagen IV, IGF1, IL-2, PKC, Smad2,4, TGF-ßR1, 2
miR-411	AMPK, Bcl-2, GSK3b, HGF, IGF1, IGF1R, IL-1a, MMP-7, PDGF, PTEN, Smad4, Smurf1
miR-495	AMPK Bcl-2, Caspase 8, CD8b, Collagen IV, FAS, GSK3B, Hexokinase2, HGF, IGF1, IGFR1,IL-1ß, IL-1R, IL-6, IRS1,2, JAK3, LDL-R, Leptin, Leptin R, MMP-14, PDGFa, PDGFRa, PI3K, PKC, PPARa, PTEN, Smad2, 4, Smurf1, TGF-ß1, TGF-ßR1, R2

The boldface genes are frequently predicted as targets for more than four of these seven miRNAs. The standard nomenclature for each of the abbreviations used in this table is listed in S3 Table.